Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/102492
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleA Novel Sunscreen Agent Having Antimelanoma Activitypt_BR
dc.contributor.authorNogueira M.A.pt_BR
dc.contributor.authorMagalhaes E.G.pt_BR
dc.contributor.authorMagalhaes A.F.pt_BR
dc.contributor.authorBiloti D.N.pt_BR
dc.contributor.authorLaverde Jr. A.pt_BR
dc.contributor.authorPessine F.B.T.pt_BR
dc.contributor.authorCarvalho J.E.pt_BR
dc.contributor.authorKohn L.K.pt_BR
dc.contributor.authorAntonio M.A.pt_BR
dc.contributor.authorMarsaioli A.J.pt_BR
unicamp.authorNogueira, M.A., Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, SP, Brazil, Faculdade de Farmácia, Univ. Estadual do Oeste do Parana, 85814-110 Cascavel, PR, Brazilpt_BR
unicamp.authorMagalhães, E.G., Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorMagalhães, A.F., Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorBiloti, D.N., Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorLaverde Jr., A., Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorPessine, F.B.T., Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorCarvalho, J.E., Ctro. Pluridisciplinar Pesq. Q., Universidade Estadual de Campinas, CP 6171, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorKohn, L.K., Ctro. Pluridisciplinar Pesq. Q., Universidade Estadual de Campinas, CP 6171, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorAntônio, M.A., Ctro. Pluridisciplinar Pesq. Q., Universidade Estadual de Campinas, CP 6171, 13083-970 Campinas, SP, Brazilpt_BR
unicamp.authorMarsaioli, A.J., Instituto de Química, Universidade Estadual de Campinas, CP 6154, 13083-970 Campinas, SP, Brazilpt_BR
dc.description.abstractA novel series of eight dibenzoylmethane derivatives having both sunscreen and cytotoxic activity has been obtained by derivatizing commercial dibenzoyl methanes. Four human cancer cell lines (MCF 7 (breast), NCI ADR (breast expressing the multidrug resistance phenotype), NCI 460 (lung) and UACC 62 (melanoma)) were used for the cytotoxic assay. Eight among the 19 dibenzoylmethane derivatives showed cytotoxicity against these four cell lines. Absorption spectroscopies revealed that these compounds can be used as sunscreens against UV radiation. © 2003 Éditions scientifiques et médicales Elsevier SAS. All rights reserved.en
dc.relation.ispartofFarmacopt_BR
dc.date.issued2003pt_BR
dc.identifier.citationFarmaco. , v. 58, n. 11, p. 1163 - 1169, 2003.pt_BR
dc.language.isoenpt_BR
dc.description.volume58pt_BR
dc.description.issuenumber11pt_BR
dc.description.firstpage1163pt_BR
dc.description.lastpage1169pt_BR
dc.rightsfechadopt_BR
dc.sourceScopuspt_BR
dc.identifier.issn0014827Xpt_BR
dc.identifier.doi10.1016/S0014-827X(03)00195-2pt_BR
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-10744232774&partnerID=40&md5=952044cfef256cde5c31851bef696781pt_BR
dc.date.available2015-06-30T17:31:59Z
dc.date.available2015-11-26T14:11:03Z-
dc.date.accessioned2015-06-30T17:31:59Z
dc.date.accessioned2015-11-26T14:11:03Z-
dc.description.provenanceMade available in DSpace on 2015-06-30T17:31:59Z (GMT). No. of bitstreams: 1 2-s2.0-10744232774.pdf: 566857 bytes, checksum: e4bd761ad4ed6f70d5ac6c04ea2dfeb2 (MD5) Previous issue date: 2003en
dc.description.provenanceMade available in DSpace on 2015-11-26T14:11:03Z (GMT). No. of bitstreams: 2 2-s2.0-10744232774.pdf: 566857 bytes, checksum: e4bd761ad4ed6f70d5ac6c04ea2dfeb2 (MD5) 2-s2.0-10744232774.pdf.txt: 23714 bytes, checksum: 84fb70328586f3f56b98ce94b47e89d4 (MD5) Previous issue date: 2003en
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/102492
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/102492-
dc.identifier.idScopus2-s2.0-10744232774pt_BR
dc.description.referenceVan Der Leun, J.C., UV radiation from sunlight: Summary, conclusions and recommendations (1996) J. Photochem. Photobiol. B: Biol., 35, pp. 237-244pt_BR
dc.description.referenceSingletary, K., MacDonald, C., Iovinelli, M., Fisher, C., Wallig, M., Effect of the beta-diketones diferuloylmethane (curcumin) and dibenzoylmethane on rat mammary DNA adducts and tumors induced by 7,12-dimethylbenz[a]anthracene (1998) Carcinogenesis, 19, pp. 1039-1043pt_BR
dc.description.referenceJackson, K.M., DeLeon, M., Verret, R.C., Harris, B.W., Dibenzoylmethane induces cell cycle deregulation in human prostate cancer cells (2002) Cancer Lett., 178, pp. 161-165pt_BR
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dc.description.referenceMagalhães, A.F., Tozzi, A.M.A., Magalhães, G.E., Blanco, I.S., Nogueira, M.A., Three dibenzoylmethane derivatives from Lonchocarpus species (1997) Phytochemistry, 46, pp. 1029-1033pt_BR
dc.description.referenceMagalhães, A.F., Tozzi, A.M.A., Magalhães, E.G., Nogueira, M.A., Floréz, R.V.J., Ensayos biológicos con extractos obtenidos de raíces de Lonchocarpus latifolius (Willd) D.C. de um nuevo dibenzoilmetano aislado (1998) Rev. Ceres, 45, pp. 351-358pt_BR
dc.description.referenceAraújo, A.C.V., Almeida, F.V., Bieber, L.W., The synthesis of malonic esters: A new procedure for a classical reaction (1996) Quim. Nova, 19, pp. 79-81pt_BR
dc.description.referenceBiloti, D.N., Reis, M.M., Ferreira, M.M.C., Pessine, F.B.T., Photochemical behavior under UVA radiation of β-cyclodextrin included Parsol ® 1789 with a chemometric approach (1999) J. Mol. Struct., 480-481, pp. 557-561pt_BR
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