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Type: Artigo de periódico
Title: Absolute Ethanol And 5% Ethanolamine Oleate Are Comparable For Sclerotherapy Of Esophageal Varices.
Author: Meirelles-Santos, J O
Carvalho, A F
Callejas-Neto, F
Magna, L A
Yamanaka, A
Zeitune, J M
Brandalise, N A
Ferraz, J G
Abstract: Endoscopic sclerotherapy is widely accepted as an effective treatment for the eradication of esophageal varices in patients with portal hypertension and a history of upper gastrointestinal bleeding. The objective of this study was to assess the effectiveness and safety of absolute ethanol as an alternative sclerosing agent to the commonly used 5% ethanolamine oleate. One hundred fifty-seven patients with portal hypertension and a history of variceal bleeding were randomly assigned to sclerotherapy with absolute ethanol (n = 66) or 5% ethanolamine oleate (n = 91) between January 1992 and July 1994. Once eradication was achieved, these patients were prospectively followed until September 1998. Sclerotherapy with both sclerosants resulted in similar eradication rates (approximately 90%), with comparable numbers of sessions required for eradication (5.4 and 5.9 sessions for absolute ethanol and 5% ethanolamine oleate, respectively). Similar complication and recurrent bleeding rates were observed among both groups. Sclerotherapy with absolute ethanol is as effective as with 5% ethanolamine oleate in preventing further bleeding in patients with portal hypertension.
Subject: Adult
Esophageal And Gastric Varices
Follow-up Studies
Gastrointestinal Hemorrhage
Hypertension, Portal
Middle Aged
Prospective Studies
Citation: Gastrointestinal Endoscopy. v. 51, n. 5, p. 573-6, 2000-May.
Rights: fechado
Date Issue: 2000
Appears in Collections:Unicamp - Artigos e Outros Documentos

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