Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/200665
Type: Artigo de periódico
Title: Influence Of Blood Pressure Profile On Frailty Phenotype In Community-dwelling Elders In Brazil - Fibra Study.
Author: Fattori, A
Santimaria, M R
Alves, R M A
Guariento, M E
Neri, A L
Abstract: Frailty is a clinical condition associated with pathological aging and biological vulnerability. In the spectrum of events related to frailty, aging of the cardiocirculatory system and abnormalities in arterial blood pressure (BP) partly explain the changes in tissue perfusion and, potentially, the decrease in physiological reserves. This study investigated the relationship between BP levels, systemic arterial hypertension (SAH) and the frailty phenotype by analyzing frailty criteria in a cross-sectional model into the FIBRA network, a populational sample of community-dwelling elders in Southeastern Brazil. Study participants with ≥65 years were selected by probabilistic sampling of residents in the urban area of the municipality of Campinas (n=900). Considering frailty as a whole and the difference between genders, there was a greater proportion of frail or pre-frail individuals among women than men. Analysis of individual frailty criteria showed that weight loss and fatigue were more common among women (18.3% vs. 12.5%, p=0.034 and 22.5% vs. 11.9%, p<0.001, respectively). Comparison of individuals with or without SAH failed to reveal any differences related to frailty criteria. Nevertheless, averages of diastolic blood pressure (DBP) and mean arterial blood pressure values were lower among elderly individuals with reduced grip strength, physical activity and the frailty classification as a whole (OR 0.986, IC 0.975-0.997) (for every 1 mmHg reduction in MBP values, the likelihood of being frail increased 1.4%). Our findings corroborate the relationship between BP values and frailty in the elderly and contribute to an understanding of the pathophysiological mechanisms of the syndrome.
Subject: Age Factors
Aged
Aged, 80 And Over
Blood Pressure
Brazil
Cross-sectional Studies
Female
Frail Elderly
Geriatric Assessment
Humans
Hypertension
Male
Phenotype
Prevalence
Retrospective Studies
Citation: Archives Of Gerontology And Geriatrics. v. 56, n. 2, p. 343-9
Rights: fechado
Identifier DOI: 10.1016/j.archger.2012.08.004
Address: http://www.ncbi.nlm.nih.gov/pubmed/22939428
Appears in Collections:Unicamp - Artigos e Outros Documentos

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