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Type: Artigo
Title: Stability, Purification, And Applications Of Bromelain: A Review
Author: de Lencastre Novaes
Leticia Celia; Jozala
Angela Faustino; Lopes
Andre Moreni; Santos-Ebinuma
Valeria de Carvalho; Mazzola
Priscila Gava; Pessoa Junior
Abstract: Bromelain is a cysteine protease found in pineapple tissue. Because of its anti-inflammatory and anti-cancer activities, as well as its ability to induce apoptotic cell death, bromelain has proved useful in several therapeutic areas. The market for this protease is growing, and several studies exploring various properties of this molecule have been reported. This review aims to compile this data, and summarize the main findings on bromelain in the literature to date. The physicochemical properties and stability of bromelain under different conditions are discussed. Several studies on the purification of bromelain from crude extracts using a wide range of techniques such as liquid-liquid extractions by aqueous two-phase system, ultrafiltration, precipitation, and chromatography, have been reported. Finally, the various applications of bromelain are presented. This review therefore covers the main properties of bromelain, aiming to provide an up-to-date compilation of the data reported on this enzyme. (c) 2015 American Institute of Chemical Engineers Biotechnol. Prog., 32:5-13, 2016
Subject: Bromelain
Downstream Processes
Editor: Wiley-Blackwell
Citation: Biotechnology Progress. Wiley-blackwell, v. 32, p. 5 - 13, 2016.
Rights: fechado
Identifier DOI: 10.1002/btpr.2190
Date Issue: 2016
Appears in Collections:Unicamp - Artigos e Outros Documentos

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