Please use this identifier to cite or link to this item:
Type: Artigo
Title: Coupling single-drop microextraction with SERS: a demonstration using p-MBA on gold nanohole array substrate
Author: Santos, Elias B.
Valsecchi, Chiara
Goncalves, Jaderson L. S.
Avila, Luis F.
Menezes, Jacson W.
Abstract: Single-drop microextraction (SDME) was coupled with surface-enhanced Raman scattering (SERS) to provide sample extraction and pre-concentration for detection of analyte at low concentrations. A gold nanohole array substrate (AuNHAS), fabricated by interference lithography, was used as SERS substrate and para-mercaptobenzoic acid (p-MBA) was tested as a probe molecule, in the concentration range 10(-8)-10(-4) mol L-1. With this approach, a limit of 10(-7) mol L-1 was clearly detected. To improve the detection to lower p-MBA concentration, as 10(-8) mol L-1, the SDME technique was applied. The p-MBA Raman signature was detected in two performed extractions and its new concentration was determined to be similar to 4.6 x 10(-5) mol L-1. This work showed that coupling SDME with SERS allowed a rapid (5 min) and efficient pre-concentration (from 10 8 mol L-1 to 10(-5) mol L-1), detection, and quantification of the analyte of interest, proving to be an interesting analytical tool for SERS applications
Subject: Espalhamento Raman intensificado por superfície
Country: Suíça
Editor: MDPI
Rights: Aberto
Identifier DOI: 10.3390/s19204394
Date Issue: 2019
Appears in Collections:FT - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
000497864700042.pdf2.29 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.