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Type: Artigo de periódico
Title: Reactive Post-Radiotherapy Bone Formation in the Maxilla
Author: Mariano, FV
Gondak, RO
Santos-Silva, AR
Correa, MB
de Almeida, OP
Lopes, MA
Abstract: Objective: High-dose radiation therapy affects bone metabolism, and therefore post-radiotherapy bone formation is an uncommon finding. This case describes an unusual ossification in the maxillary region identified after head and neck radiotherapy. Results: A 45-year-old female patient was submitted to maxillary surgical resection and orbital exenteration due to squamous cell carcinoma. Radiotherapy post-surgery was performed because of compromised surgical margins. After 4 months of the conclusion of radiotherapy, the patient presented a bone exposition at surgical site. Surprisingly, the oral examination and computed tomography revealed a new formation of the right palatine vault and bone formation filling the nasal and orbital cavity. The incisional biopsy discarded residual disease or osteoradionecrosis and showed normal tissue. Conclusions: To the best of the authors' knowledge, this is the first case of wide bone formation as an early effect of head and neck radiotherapy.
Subject: Reactive bone
head and neck
Country: EUA
Editor: Lippincott Williams & Wilkins
Citation: Journal Of Craniofacial Surgery. Lippincott Williams & Wilkins, v. 24, n. 1, n. E43, n. E45, 2013.
Rights: fechado
Identifier DOI: 10.1097/SCS.0b013e31826d0015
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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