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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleInterference of dexamethasone in the pulmonary cycle of Strongyloides venezuelensis in ratspt_BR
dc.contributor.authorTefe-Silva, Cpt_BR
dc.contributor.authorSouza, DIpt_BR
dc.contributor.authorUeta, MTpt_BR
dc.contributor.authorFloriano, EMpt_BR
dc.contributor.authorFaccioli, LHpt_BR
dc.contributor.authorRamos, SGpt_BR
unicamp.author.emailsgramos@fmrp.usp.brpt_BR
unicamp.authorRamos, Simone G. Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Patol, BR-14049900 Sao Paulo, Brazil Univ Estadual Campinas, Inst Biol, Dept Parasitol, BR-13073970 Sao Paulo, Brazil Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, BR-14049900 Sao Paulo, Brazilpt_BR
dc.subject.wosEndothelial Growth-factorpt_BR
dc.subject.wosHuman Eosinophilspt_BR
dc.subject.wosAirway Hyperresponsivenesspt_BR
dc.subject.wosGastrointestinal-tractpt_BR
dc.subject.wosStercoralis Infectionpt_BR
dc.subject.wosAsthmatic Airwayspt_BR
dc.subject.wosGene-expressionpt_BR
dc.subject.wosIn-vitropt_BR
dc.subject.wosTgf-betapt_BR
dc.subject.wosInflammationpt_BR
dc.description.abstractThe aim of this study was to investigate the interference of a daily treatment of dexamethasone in the pulmonary cycle of Strongyloides venezuelensis infection in rats. Three principal effects were found: 1) increased alveolar hemorrhagic inflammation provoked by the passage of larvae into alveolar spaces; 2) significant decrease of eosinophil and mast cell migration to the axial septum of the lungs; and 3) impaired formation of the reticular fiber network, interfering with granuloma organization. This study showed that the use of drugs with immunomodulatory actions, such as dexamethasone, in addition to interfering with the morbidity from the pulmonary cycle of S. venezuelensis infection, may contribute to showing the mechanisms involved in its pathogenesis.pt
dc.description.noteo TEXTO COMPLETO DESTE ARTIGO, ESTARÁ DISPONÍVEL À PARTIR DE AGOSTO DE 2015.pt
dc.relation.ispartofAmerican Journal Of Tropical Medicine And Hygienept_BR
dc.relation.ispartofabbreviationAm. J. Trop. Med. Hyg.pt_BR
dc.publisher.cityMcleanpt_BR
dc.publisher.countryEUApt_BR
dc.publisherAmer Soc Trop Med & Hygienept_BR
dc.date.issued2008pt_BR
dc.date.monthofcirculationOCTpt_BR
dc.identifier.citationAmerican Journal Of Tropical Medicine And Hygiene. Amer Soc Trop Med & Hygiene, v. 79, n. 4, n. 571, n. 578, 2008.pt_BR
dc.language.isoenpt_BR
dc.description.volume79pt_BR
dc.description.issuenumber4pt_BR
dc.description.firstpage571pt_BR
dc.description.lastpage578pt_BR
dc.rightsembargopt_BR
dc.sourceWeb of Sciencept_BR
unicamp.cruespUSPpt_BR
dc.identifier.issn0002-9637pt_BR
dc.identifier.wosidWOS:000259858000017pt_BR
dc.date.available2014-07-30T14:33:56Z
dc.date.available2015-11-26T18:06:52Z-
dc.date.accessioned2014-07-30T14:33:56Z
dc.date.accessioned2015-11-26T18:06:52Z-
dc.description.provenanceMade available in DSpace on 2014-07-30T14:33:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2008en
dc.description.provenanceMade available in DSpace on 2015-11-26T18:06:52Z (GMT). No. of bitstreams: 2 WOS000259858000017.pdf: 1439370 bytes, checksum: 9bbb5598cdc7de17c6182b67caed356d (MD5) WOS000259858000017.pdf.txt: 40039 bytes, checksum: 187867997d1b4db2a4a1d07cdbb75be7 (MD5) Previous issue date: 2008en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/60426
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/60426-
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