Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/66636
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dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titleFabrication of a multichannel PDMS/glass analytical microsystem with integrated electrodes for amperometric detectionpt_BR
dc.contributor.authorMoreira, NHpt_BR
dc.contributor.authorde Almeida, ALDJpt_BR
dc.contributor.authorPiazzeta, MHDOpt_BR
dc.contributor.authorde Jesus, DPpt_BR
dc.contributor.authorDeblire, Apt_BR
dc.contributor.authorGobbi, ALpt_BR
dc.contributor.authorda Silva, JAFpt_BR
unicamp.author.emailgobbi@lnls.brpt_BR
unicamp.author.emailfracassi@iqm.unicamp.brpt_BR
unicamp.authorde Jesus, Dosil Pereira Deblire, Ariane Fracassi da Silva, Jose Alberto Univ Estadual Campinas, UNICAMP, Inst Chem, BR-13083970 Campinas, SP, Brazilpt_BR
unicamp.authorMoreira, Ney Henrique de Jesus de Almeida, Andre Luis de Oliveira Piazzeta, Maria Helena Gobbi, Angelo Luiz Brazilian Synchrotron Light Lab, Lab Microfabricat, Campinas, SP, Brazilpt_BR
dc.subject.wosTotal Analysis Systemspt_BR
dc.subject.wosCapillary-electrophoresispt_BR
dc.subject.wosElectrochemical Detectionpt_BR
dc.subject.wosMicrofluidic Systemspt_BR
dc.subject.wosSample Introductionpt_BR
dc.subject.wosMicrochippt_BR
dc.subject.wosPoly(dimethylsiloxane)pt_BR
dc.subject.wosParallelpt_BR
dc.subject.wosDevicespt_BR
dc.subject.wosChippt_BR
dc.description.abstractThe fabrication process of novel multichannel microfluidic devices with integrated electrodes for amperometric detection is described. Soft-lithography, lift-off and O(2) plasma surface activation sealing techniques were employed for rapid prototyping of cost effective PDMS/glass microchips. The capabilities of the proposed microdevices were demonstrated by the electrooxidation of hydroquinone and N-acetyl-p-aminophenol (APAP) on a Au working electrode at + 800 mV and + 700 mV, respectively, against a Au pseudo reference electrode, and of thiocyanate on a Cu working electrode at + 700 mV against a Ag/AgCl (KCl saturated) reference electrode. Linear response over the range up to 1.0 mmol L(-1) for APAP and up to 4.0 mmol L(-1) for hydroquinone and thiocyanate were verified through calibration curves with correlation coefficients greater than 0.97 (minimum of five data points). The sensitivities for hydroquinone, thiocyanate, and APAP were 28, 19, and 78 mu A mol(-1) L, respectively. Under the experimental conditions used, the estimated limits of detection were 0.21, 0.95, and 0.12 mmol L(-1) for hydroquinone, thiocyanate and APAP, respectively. The geometries of the devices were designed to allow fast calibration procedures and reliable results for in-field applications. Exerting a strong influence over the device performance, the sealing process was greatly enhanced by depositing auxiliary TiSiO(2) thin-films. The general performance of the system was verified by amperometric assays of N-acetyl-p-aminophenol standard solutions, and the influences exerted by the present fabrication methods regarding reproducibility and reliability are addressed. The proposed device was successfully applied in the determination of the concentration of APAP in two commercial formulations.pt
dc.description.noteo TEXTO COMPLETO DESTE ARTIGO, ESTARÁ DISPONÍVEL À PARTIR DE AGOSTO DE 2015.pt
dc.relation.ispartofLab On A Chippt_BR
dc.relation.ispartofabbreviationLab Chippt_BR
dc.publisher.cityCambridgept_BR
dc.publisher.countryInglaterrapt_BR
dc.publisherRoyal Soc Chemistrypt_BR
dc.date.issued2009pt_BR
dc.identifier.citationLab On A Chip. Royal Soc Chemistry, v. 9, n. 1, n. 115, n. 121, 2009.pt_BR
dc.language.isoenpt_BR
dc.description.volume9pt_BR
dc.description.issuenumber1pt_BR
dc.description.firstpage115pt_BR
dc.description.lastpage121pt_BR
dc.rightsembargopt_BR
dc.sourceWeb of Sciencept_BR
dc.identifier.issn1473-0197pt_BR
dc.identifier.wosidWOS:000262649400016pt_BR
dc.identifier.doi10.1039/b807409gpt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorship1Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorship1Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.date.available2014-11-13T23:03:10Z
dc.date.available2015-11-26T16:03:00Z-
dc.date.accessioned2014-11-13T23:03:10Z
dc.date.accessioned2015-11-26T16:03:00Z-
dc.description.provenanceMade available in DSpace on 2014-11-13T23:03:10Z (GMT). No. of bitstreams: 1 WOS000262649400016.pdf: 509458 bytes, checksum: 470d84602b4fd3efb2d99ebbd78f9b50 (MD5) Previous issue date: 2009en
dc.description.provenanceMade available in DSpace on 2015-11-26T16:03:00Z (GMT). No. of bitstreams: 2 WOS000262649400016.pdf: 509458 bytes, checksum: 470d84602b4fd3efb2d99ebbd78f9b50 (MD5) WOS000262649400016.pdf.txt: 37023 bytes, checksum: b084cfcb0f89489f420d950966372617 (MD5) Previous issue date: 2009en
dc.identifier.urihttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/66636pt_BR
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/66636
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/66636-
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