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Type: Artigo de periódico
Title: The influence of protecting groups on the diastereoselectivity of catalytic heterogeneous hydrogenation of Baylis-Hillman adducts
Author: Coelho, F
Almeida, WP
Mateus, CR
Furtado, LD
Gouveia, JCF
Abstract: In this communication we describe our recent results from a study on catalytic heterogeneous hydrogenation reactions of Baylis-Hillman adducts. Depending on the protecting groups used on the secondary hydroxyl group of these adducts, it is possible to obtain a high degree of diastereoselection. For silylated Baylis-Hillman adducts a high syn diastereoselectivity has been obtained. However, when secondary Baylis-Hillman hydroxyl groups were unprotected or protected as acetate a moderate anti selectivity was attained. The adducts protected as methyl ether gave poor syn diastereoselectivity.
Subject: Baylis-Hillman
heterogeneous hydrogenation
Country: EUA
Editor: Arkat Usa Inc
Citation: Arkivoc. Arkat Usa Inc, n. 443, n. 467, 2003.
Rights: aberto
Date Issue: 2003
Appears in Collections:Unicamp - Artigos e Outros Documentos

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