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Type: Artigo de periódico
Title: Study of kinetic parameters in a mechanistic model for bioethanol production through a screening technique and optimization
Author: de Andrade, RR
Rivera, EC
Atala, DIP
Maciel, R
Maugeri, F
Costa, AC
Abstract: The accurate description of the kinetics and robust modeling of biotechnological processes can only be achieved by incorporating reliable methodologies to easily update the model when there are changes in operational conditions. The purpose of this work is to provide a systematic approach with which to perform model parameters screening and updating in biotechnological processes. Batch experiments are performed to develop a mechanistic model, considering the effect of temperature on the kinetics, and further experiments (batch fermentations using sugar cane molasses from a different harvest) are used to validate the effectiveness of screening before parameters updating. The reduction in the number of kinetic parameters to be re-estimated enabled by the screening procedure reduces significantly the complexity of the optimization, which makes the updating procedure to be significantly quicker, while resulting in accurate performance of the updated model.
Subject: Bioreactors
Parameter estimation
Placket-Burman design
Country: EUA
Editor: Springer
Citation: Bioprocess And Biosystems Engineering. Springer, v. 32, n. 5, n. 673, n. 680, 2009.
Rights: fechado
Identifier DOI: 10.1007/s00449-008-0291-8
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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