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Type: Artigo de periódico
Title: Antimicrobial potential of Coriandrum sativum L. against different Candida species in vitro
Author: Begnami, AF
Duarte, MCT
Furletti, V
Rehder, VLG
Abstract: The aim of this study was to evaluate the chemical and antifungal activity of the essential oil from Coriandrum sativum L (Apiaceae) against different Candida species. The essential oil (EO) was obtained by hydrodistillation and submitted to dry-column chromatography, resulting in six fractions, which were then submitted to TLC and GC-MS analysis. The main compounds identified were alcohols: 1-decanol (24.20%): 2E-decenol (18.00%); 2Z-dodecenol (17.60%): and aldehydes (89%). Antibacterial activity of the EO and its fractions was tested against five species of Candida albicans. The EO showed antimicrobial activity against all the species of Candida tested, except for Candida tropicalis CBS 94. Fractions 4 and 6 had a greater antibiotic spectrum, probably due to the presence of such alcohols as 3-hexenol, 1-decanol, 2E-decenol and 2Z-dodecenol. In conclusion, the EO and its fractions could be used as potential antimicrobial agents to treat or prevent Candida yeast infections. (C) 2009 Published by Elsevier Ltd.
Subject: Essential oil
Antimicrobial activity
Coriandrum sativum
Country: Inglaterra
Editor: Elsevier Sci Ltd
Citation: Food Chemistry. Elsevier Sci Ltd, v. 118, n. 1, n. 74, n. 77, 2010.
Rights: fechado
Identifier DOI: 10.1016/j.foodchem.2009.04.089
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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