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Type: Artigo de periódico
Title: Leydig Cell Tumour in a 46,XX Child with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
Author: Lazaro, APP
de Lacerda, AM
Ghiaroni, J
de Miranda, LCD
Vidal, APA
Collett-Solberg, PF
Michelatto, DD
Mello, MP
Guimaraes, MM
Abstract: Case Report: A 10-year-old male was referred to our institution due to short stature and bilateral cryptorchidism and reported pubic hair development and acne since the age of 4 years. Laboratory and molecular genetic tests indicated congenital adrenal hyperplasia due to 21-hydroxylase deficiency. After treatment with prednisone, adrenal hormones normalised but testosterone remained elevated. Magnetic resonance imaging of the abdomen due to cryptorchidism revealed uterus and adnexal attachments, a prostate and poorly defined nodules on the iliac chains. Upon exploratory laparotomy, a hysterectomy, bilateral oophorectomy and resection of a peri-adnexal nodular lesion on the patient's right side were performed. Histopathology of the nodule mass was compatible with a Leydig cell tumour with a low proliferation rate according to Ki67. Copyright (c) 2013 S. Karger AG, Basel
Subject: Congenital adrenal hyperplasia
Leydig cell tumour
Country: Suíça
Editor: Karger
Citation: Hormone Research In Paediatrics. Karger, v. 79, n. 3, n. 179, n. 184, 2013.
Rights: fechado
Identifier DOI: 10.1159/000346899
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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