Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUniversidade Estadual de Campinaspt_BR
dc.typeArtigo de periódicopt_BR
dc.titlePostural Changes May Influence Popliteal Atherosclerosis by Modifying Local Circumferential Wall Tensionpt_BR
dc.contributor.authorGemignani, Tpt_BR
dc.contributor.authorMatos-Souza, JRpt_BR
dc.contributor.authorCoelho, ORpt_BR
dc.contributor.authorFranchini, KGpt_BR
dc.contributor.authorNadruz, Wpt_BR
unicamp.authorGemignani, Tiago Matos-Souza, Jose R. Coelho, Otavio R. Franchini, Kleber G. Nadruz, Wilson, Jr. Univ Estadual Campinas, Sch Med, Dept Internal Med, Campinas, SP, Brazilpt_BR
dc.subjectblood pressurept_BR
dc.subjectbody posturept_BR
dc.subjectcircumferential wall tensionpt_BR
dc.subjectIntima-media thicknesspt_BR
dc.subject.wosIntima-media Thicknesspt_BR
dc.subject.wosHemodynamic Forcespt_BR
dc.subject.wosPulse Pressurept_BR
dc.description.abstractAtherosclerosis of peripheral arteries typically affects vessels of the lower limbs, suggesting that local hemodynamic stimuli play a role in this process. Our study evaluated the effects of body postural changes on carotid and popliteal blood pressure, circumferential wall tension (CWT) and arterial strain, and investigated the relationship between such hemodynamic parameters and Intima-media thickness (IMT) of these arteries. One hundred seventeen nondiabetic, nonhypertensive, nonsmoker subjects (48 men and 69 women) were enrolled and had their blood pressure measured in the arm and calf in supine and orthostatic positions. Echo-doppler analysis evaluated the common carotid and popliteal arteries after blood pressure measurements, while CWT was calculated according to Laplace's law. The results showed that changing from supine to orthostatic posture Increased blood pressure and CWT In popliteal but not In carotid arteries. Partial correlation analysis adjusted for age and body mass index revealed no major relationship between IMT of the studied vessels and local blood pressure or arterial strain. Conversely, supine and orthostatic CWT exhibited comparable correlation coefficients with carotid IMT, while orthostatic CWT displayed a stronger relationship with popliteal IMT than with supine CWT. These results were confirmed by multiple linear regression analysis that Included age, sex, body mass Index, lipid fractions and glucose as independent variables. Overall, our results indicate that orthostatic CWT is a stronger hemodynamic predictor of popliteal IMT than supine CWT, suggesting that erectile posture may be a potential risk factor for popliteal atherosclerosis because it increases the local hemodynamic burden. (Hypertens Res 2008; 31: 2059-2064)pt
dc.relation.ispartofHypertension Researchpt_BR
dc.relation.ispartofabbreviationHypertens. Res.pt_BR
dc.publisherNature Publishing Grouppt_BR
dc.identifier.citationHypertension Research. Nature Publishing Group, v. 31, n. 11, n. 2059, n. 2064, 2008.pt_BR
dc.sourceWeb of Sciencept_BR
dc.description.provenanceMade available in DSpace on 2014-11-14T21:54:16Z (GMT). No. of bitstreams: 1 WOS000262968800010.pdf: 55830 bytes, checksum: 85651c9341d6a8d65986e762c657404c (MD5) Previous issue date: 2008en
dc.description.provenanceMade available in DSpace on 2015-11-26T17:17:27Z (GMT). No. of bitstreams: 2 WOS000262968800010.pdf: 55830 bytes, checksum: 85651c9341d6a8d65986e762c657404c (MD5) WOS000262968800010.pdf.txt: 30191 bytes, checksum: 780092036119e703471d51836f4e62d8 (MD5) Previous issue date: 2008en
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000262968800010.pdf54.52 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.