Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/85342
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dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titleLeydig Cell Number And Sperm Production Decrease Induced By Chronic Ametryn Exposure: A Negative Impact On Animal Reproductive Healthpt_BR
dc.contributor.authorDantas T.A.pt_BR
dc.contributor.authorCancian G.pt_BR
dc.contributor.authorNeodini D.N.R.pt_BR
dc.contributor.authorMano D.R.S.pt_BR
dc.contributor.authorCapucho C.pt_BR
dc.contributor.authorPredes F.S.pt_BR
dc.contributor.authorPulz R.B.pt_BR
dc.contributor.authorPigoso A.A.pt_BR
dc.contributor.authorDolder H.pt_BR
dc.contributor.authorSeveri-Aguiar G.D.C.pt_BR
unicamp.authorDolder, H., Laboratório de Biologia da Reprodução, Departamento de Biologia Estrutural e Funcional, Universidade Estadual de Campinas – UNICAMP, CP. 6109Campinas, SP, Brazilpt_BR
unicamp.author.externalDantas, T.A., Programa de Pós-Graduação em Ciências Biomédicas, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
unicamp.author.externalCancian, G., NUCISA – Núcleo de Ciências da Saúde, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
unicamp.author.externalNeodini, D.N.R., NUCISA – Núcleo de Ciências da Saúde, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
unicamp.author.externalMano, D.R.S., NUCISA – Núcleo de Ciências da Saúde, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
unicamp.author.externalCapucho, C., NUCISA – Núcleo de Ciências da Saúde, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
unicamp.author.externalPredes, F.S., Universidade Estadual do Paraná- UNESPAR/Campus Paranaguá, Rua Comendador Correa Junior, 117, CentroParanaguá, PR, Brazilpt
unicamp.author.externalPulz, R.B., NUCISA – Núcleo de Ciências da Saúde, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
unicamp.author.externalPigoso, A.A., NUCISA – Núcleo de Ciências da Saúde, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
unicamp.author.externalSeveri-Aguiar, G.D.C., Programa de Pós-Graduação em Ciências Biomédicas, Centro Universitário Hermínio Ometto UNIARARAS, Avenida Dr. Maximiliano Barutto, n° 500, Jd. UniversitárioAraras, SP, Brazilpt
dc.description.abstractAmetryn is an herbicide used to control broadleaf and grass weeds and its acute and chronic toxicity is expected to be low. Since toxicological data on ametryn is scarce, the aim of this study was to evaluate rat reproductive toxicity. Thirty-six adult male Wistar rats (90 days) were divided into three groups: Co (control) and T1 and T2 exposed to 15 and 30 mg/kg/day of ametryn, respectively, for 56 days. Testicular analysis demonstrated that ametryn decreased sperm number per testis, daily sperm production, and Leydig cell number in both treated groups, although little perceptible morphological change has been observed in seminiferous tubule structure. Lipid peroxidation was higher in group T2, catalase activity decreased in T1 group, superoxide dismutase activity diminished, and a smaller number of sulphydryl groups of total proteins were verified in both exposed groups, suggesting oxidative stress. These results showed negative ametryn influence on the testes and can compromise animal reproductive performance and survival.en
dc.relation.ispartofEnvironmental Science and Pollution Researchpt_BR
dc.publisherSpringer Verlagpt_BR
dc.date.issued2015pt_BR
dc.identifier.citationEnvironmental Science And Pollution Research. Springer Verlag, v. , n. , p. - , 2015.pt_BR
dc.language.isoenpt_BR
dc.rightsfechadopt_BR
dc.sourceScopuspt_BR
dc.identifier.issn9441344pt_BR
dc.identifier.doi10.1007/s11356-014-4010-5pt_BR
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84922359625&partnerID=40&md5=3a22cdc88d2273b9202ee9fe9aac2489pt_BR
dc.date.available2015-06-25T12:52:07Z
dc.date.available2015-11-26T14:55:27Z-
dc.date.accessioned2015-06-25T12:52:07Z
dc.date.accessioned2015-11-26T14:55:27Z-
dc.description.provenanceMade available in DSpace on 2015-06-25T12:52:07Z (GMT). No. of bitstreams: 1 2-s2.0-84922359625.pdf: 1117004 bytes, checksum: 516985dab37feb3c4c60add8a89f1253 (MD5) Previous issue date: 2015en
dc.description.provenanceMade available in DSpace on 2015-11-26T14:55:27Z (GMT). No. of bitstreams: 2 2-s2.0-84922359625.pdf: 1117004 bytes, checksum: 516985dab37feb3c4c60add8a89f1253 (MD5) 2-s2.0-84922359625.pdf.txt: 37597 bytes, checksum: d419db5a6101e501e63f11936d162df9 (MD5) Previous issue date: 2015en
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/85342
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/85342-
dc.identifier.idScopus2-s2.0-84922359625pt_BR
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