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|Type:||Artigo de periódico|
|Title:||Activity Of Arrabidaea Chica (humb. & Bonpl.) Verlot Extracts Obtained By Biotechnological Processes On Fibroblast And Human Tumor Cells [atividade De Extratos De Arrabidaea Chica (humb. & Bonpl.) Verlot Obtidos Por Processos BiotecnolÓgicos Sobre A ProliferaÇÃo De Fibroblastos E CÉlulas Tumorais Humanas]|
De Oliveira Sousa I.M.
De Carvalho J.E.
|Abstract:||Arrabidaea chica (H&B) Verlot is a plant popularly known as Pariri and this species is a known source of anthocyanins, flavonoids and tannins. This report describes an approach involving enzymatic treatment prior to extraction procedures to enhance A chica crude extract anticancer activity. Anticancer activity in human cancer cell lines in vitro using a 48 h SRB cell viability assay was performed to determine growth inhibition and cytotoxic properties. The final extraction yield without enzyme treatment was higher (24.28%) compared to the enzyme-treated material (19.03%), with an enhanced aglycones anthocyanin ratio as determined by HPLC- DAD and LC-MS with direct infusion.|
|Citation:||Quimica Nova. , v. 36, n. 3, p. 431 - 436, 2013.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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