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Type: Artigo de periódico
Title: Activity Of Arrabidaea Chica (humb. & Bonpl.) Verlot Extracts Obtained By Biotechnological Processes On Fibroblast And Human Tumor Cells [atividade De Extratos De Arrabidaea Chica (humb. & Bonpl.) Verlot Obtidos Por Processos BiotecnolÓgicos Sobre A ProliferaÇÃo De Fibroblastos E CÉlulas Tumorais Humanas]
Author: Taffarello D.
Jorge M.P.
De Oliveira Sousa I.M.
Duarte M.C.T.
Figueira G.M.
Queiroz N.D.C.A.
Rodrigues R.A.F.
De Carvalho J.E.
Goes A.L.T.R.
Foglio M.A.
Riveros J.M.
Eberlin M.N.
Cabral E.C.
Abstract: Arrabidaea chica (H&B) Verlot is a plant popularly known as Pariri and this species is a known source of anthocyanins, flavonoids and tannins. This report describes an approach involving enzymatic treatment prior to extraction procedures to enhance A chica crude extract anticancer activity. Anticancer activity in human cancer cell lines in vitro using a 48 h SRB cell viability assay was performed to determine growth inhibition and cytotoxic properties. The final extraction yield without enzyme treatment was higher (24.28%) compared to the enzyme-treated material (19.03%), with an enhanced aglycones anthocyanin ratio as determined by HPLC- DAD and LC-MS with direct infusion.
Citation: Quimica Nova. , v. 36, n. 3, p. 431 - 436, 2013.
Rights: aberto
Identifier DOI: 10.1590/S0100-40422013000300014
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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